Role of membranes in the activities of antimicrobial cationic peptides.
نویسندگان
چکیده
Cationic amphiphilic peptides that are found throughout nature have very broad-spectrum activities against microbes. The initial sites of interaction are with microbial membranes. Although dogma suggests that their lethal action involves disruption of the cytoplasmic membranes, a number of cationic peptides can traverse intact membranes to interact with internal targets.
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ورودعنوان ژورنال:
- FEMS microbiology letters
دوره 206 2 شماره
صفحات -
تاریخ انتشار 2002